With his writing career tanking and his girlfriend (Abbie Cornish) casting him off, ex-druggie Eddie Morra’s (Bradley Cooper) fortunes finally turn around when he’s given a mysterious drug that provides astonishing mental powers — but its deadly side effects threaten his sanity. Adding to Eddie’s misery are shadowy businessman Carl Van Loon (Robert De Niro), who wants to exploit his new genius, and the other users willing to kill for his stash.
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